Wednesday, June 21, 2017

Classification of LIPID REDUCING DRUGS ( ANTIHYPERLIPIDAEMICS)

LIPID REDUCING DRUGS OR ANTIHYPERLIPIDAEMICS

CHEMICAL CLASSIFICATION of ANTIHYPERLIPIDAEMICS

1. STATINS CLACTONE PRODRUGS as ANTIHYPERLIPIDAEMICS

· Atrovastatin
· Prevastatin
· Simuastatin
· Lovastatin
· Fluvastatin
· Cervastatin
· Red Yeast Rice
· Rosuvastatin

2. FIBRATES as ANTIHYPERLIPIDAEMICS

· Clofibrate
· FenoFibrate
· Fenobibric Acid
· Gemfibrozie

3. BILE ACID SEQUESTRANTS as ANTIHYPERLIPIDAEMICS

· Colesevelam
· Colestipol
· Chlestyramine
4. EZETIMIBE as ANTIHYPERLIPIDAEMIC

5. NIACIN as ANTIHYPERLIPIDAEMIC

6. PHYTOSTEROLS as ANTIHYPERLIPIDAEMIC

7. ORLISTAT as ANTIHYPERLIPIDAEMIC

· Xanical

8. MISCELLNENEOUS  ANTIHYPERLIPIDAEMIC Drugs

· Dextrothyroxine Na, Probucol


CLassification of as ANTIHYPERLIPIDAEMICS ON BASIS OF MECHANISM OF ACTION

1. DRUGS DECREASING CHOLESTEROL SYNTHESIS
· STATINS
· Atrovastatin
· Fluvastatin
· Simvastatin
· Prevastatin
· Rosuvastatin
· Levostatin
2. DRUGS PREVENTING RECYCLING OF BILE ACIDS

· Colesevelam
· Colestipal
· Cholestyhamine
3. DRUGS DEVREASING CHOLESTEROL ABSORPTION

· Phytosterol
4. DRUGS INHIBITING CHOLESTREOL ABSORPTION

· Ezetimibe
5. DRUGS DECREASING ABSORPTION OF FATS (30%) FROM GUT

· Ortestat


CLassification of as ANTIHYPERLIPIDAEMICS ON BASIS OF SITE OF ACTION

1. LIVER

· Niacin
· Fibrate

2. ADIPOSE TISSUE
· Niacin
· Fibrate
3. GUT

· Orlistat
· Ezetimibe
· Phytosterol
· Bile Acid Binding Resins

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