Wednesday, June 21, 2017

CLASSIFICATION OF MUCOLYTICS & EXPECTORANTS

CLASSIFICATION OF MUCOLYTICS & EXPECTORANTS

CLASSIFICATION OF EXPECTORANTS

A) CHEMICAL CLASSIFICATION OF EXPECTORANTS:
Alkaloids = Ipecacuanha
Guasea rasbyi = Cocillana.
Glycosidal saponins = Senega, Squill.
Iodides = Sodium iodide, Potassium iodide.
B) PHARMACOLOGICAL CLASSIFICATION OF EXPECTORANTS :
i) DRUGS ACTING REFLEXLY :
Ipecacuanha, Ammonium chloride, Ammonium
bicarbonate, Guaifenesin, Cocillana, Senega,
Squill, Terpen hydrate.
ii) DRUGS ACTING DIRECTLY :
Sodium iodide and Potassium iodide.
C) THERAPEUTIC CLASSIFICATION OF EXPECTORANTS:
i) Irritant to Gastric mucosa :
Ipecacuanha, Squill, Senega, Ammonium
Chloride and Ammonium bicarbonate.
ii) Carminative use : Ammonium bicarbonate
iii) Decrease viscosity of sputum :
Guaifenesin, Sodium and Potassium iodide.
iv) Chronic bronchitis and TB: Sodium iodide.




CLASSIFICATION OF MUCOLYTICS
A) CHEMICAL CLASSIFICATION OF MUCOLYTICS:
Alkaloid derivative: Bromhexine.
Amino acid derivative: Carbocisteine.


B) PHARMACOLOGICAL CLASSIFICATION OF MUCOLYTICS:
i) Inhalational Mucolytics :
Acetylcysteine, Tyloxapol.
ii) Oral Mucolytics :
Acetylcysteine, Bromhexine, Carbocisteine,
Methylcysteine.
C) THERAPEUTIC CLASSIFICATION OF MUCOLYTICS:
i) Chronic bronchitis :
Carbocisteine, Bromhexine.
ii) Bronchial asthma :
Tyloxapol, Bromhexine
iii)Mucoviscidosis:Bromhexine, Acetylcysteine,
methylcysteine.

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