Classification of Sympathomimetics

Classification of Sympathomimetics

Classification of sympathomimetics:

A)CLassification Of Sympathomimetics According to chemical nature:

1) Catecholamines
a) Natural:
Epinephrine
Nor-epinephrine
Dopamine
b) Synthetic:
Isoprenaline
Dobutamine
Isoetharine
Hexoprenaline
2) NON-Catecholamines
Ephedrine
Pseudoephedrine
Amphetamine
Methoxamine
Mephentramine

B) CLassification of Sympathomimetics According to mode of action:

1) Direct Acting Sympathomimetics:
Epinephrine
Nor-epinephrine
Methoxamine
Xylometazoline
2) Indirect Acting Sympathomimetics:
Amphetamine
Methamphetamine
Tyramine
Mephentramine
3) Mixed Acting Sympathomimetics:
Ephedrine
Metraminol
Dopamine

C) CLassification of Sympathomimetics According to receptor selectivity:

1) Non-selective Sympathomimetics:
Epinephrine
Nor-Epinephrine
Ephedrine
Amphetamine
Metraminol
2) Mainly on alpha receptors Sympathomimetics:
Oxymetazoline
Naphazoline
Oxedrine
Phenylephrine
3) Acting mainly on beta receptors Sympathomimetics:
Isoproteronol
Orciprenaline
4) Alpha1 selective Sympathomimetics:
Methoxamine
Phenylephrine
Metraminol
Mephentramine
Midodrine
Cirazoline
5) Alpha2 selective Sympathomimetics:
Clonidine
Apraclonidine
Guanfacine
Guanabenz
Brimonidine
Alpha methyl dopa
6) Beta 1 selective Sympathomimetics:
Dobutamine
Prenalterol
7) Beta 2 selective;
a) Intermediate acting Sympathomimetics:
Albuterol
Isoetharine
Salbutamol
Terbutaline
b) Long acting Sympathomimetics:
Formoterol
Salmeterol
8) Dopamine selective:
Dopamine
Bromocriptine
Fenoldopam

D) Therapeutic classification OF Sympathomimetics:

1) Sympathomimetics used in Bronchial Asthma:
Salbutamol, ephedrine, epinephrine
2) Sympathomimetics used in  Nasal Congestion:
Naphazoline, Pseudoephedrine
3) Sympathomimetics used in  Hypotension:
Ephedrine,methxamine
4) Sympathomimetics used in  Acute anaphylatic shock:
Epinephrine
5) Sympathomimetics used in  Heart block:
Isoprenaline,ephedrine,epinephrine
6) Sympathomimetics used in  Prevention of premature labour:
Salbutamol, terbutaline
7) Sympathomimetics used as Vasodilators:
Isoxsuprine,nyldrin
8) Sympathomimetics used as CNS-stimulants:
Amphetamine,methamphetamine
9) Sympathomimetics used as Anorexic Agents:
Fenfluramine,phenmetrazine,amphetamine
10) Sympathomimetics used as  Mydriatics:
Ephedrine,epinephrine
E) Special Sympathomimetics;
Cocaine
Tyramine