Nitazoxanide covers broadly !!
rota, amoeba giardia, clostridium dificile and parvum , blastocystic hominis(protozoal)
Campylobactor jejuni (supportive)(in severe cases give azithro or quinolone)
Botulism (supportive+ botulism antitoxin if given early in disease)
shigella (supportive)(severe cases: CIPRO }}} ampicillin/TMP-SMX/,ceftriaxone,azithromycin)
Vibrio cholera (azithromycin first line )(doxy 2nd line)
B.cereus ,
staph aureus (supportive / preformed toxins)
yersinia (supportive }} if septic treat with amikacin, / TMP SMX / doxy / cipro)
amoeba (sympto ? :intestinal/hepatic abscess: metronidazole/tinidazole followed by
paromomycin/iodoquinol )
(asympto? : paromomycin/iodoquinol)
Giardia (nitazoxanide/ metronidazole/tinidazole)
Toxoplasma gondii (serology/ PCR ||||| ) (asympto? :: no t/m necessary)
sympto?::: child pyrimethamine+sulfadiazine (e folic acid)
same for pregnant and immuno compromised .
If eye involvement , add steroids.
do not forget folic acid addition because of both drugs pyri and sulfadia
Trichinella ( mebendazole/ albendazole ) add steroids in severe disease
Amanita mushroom ( supportive care for hepatic and renal functions)
Tetrodotoxin ( puffer fish) rapid ascending paralysis with death in 4 hrs ( give resp support)
campylobactor jejuni can cause:
GBS, glomerulonephritis, igA nephropathy , erythema nodosum, hemolytic anemia (not HUS) , reactive arthritis , UTI, hepatitis, pneumonia , meningtitis.
t/m: erythromycin //azithromycin )
LACTOBACILLUS GG (reduces severity and duration of ROTA virus diarrhoea)
(for a minimum period of 7 days or untill diarrhoea resolved)
Saccharomyces boulardii ( for A/B diarrhoea, and clostridium difficile diarrhoea)
(for a minimum period of 7 days or untill diarrhoea resolved)
Clostridium difficle ( hold offending AB, start metronidazole.... 2nd line is vanco./ // NT TOX //
s. boulardii )
ETEC, EPEC, EIEC (ceftrizaone, azithro , TMP-SMX , ampicillin , cipro)
never give A/B for EHEC
Amoeba ,, metronidazole follwed by iodoquinol or paromomycin
rota, amoeba giardia, clostridium dificile and parvum , blastocystic hominis(protozoal)
Campylobactor jejuni (supportive)(in severe cases give azithro or quinolone)
Botulism (supportive+ botulism antitoxin if given early in disease)
shigella (supportive)(severe cases: CIPRO }}} ampicillin/TMP-SMX/,ceftriaxone,azithromycin)
Vibrio cholera (azithromycin first line )(doxy 2nd line)
B.cereus ,
staph aureus (supportive / preformed toxins)
yersinia (supportive }} if septic treat with amikacin, / TMP SMX / doxy / cipro)
amoeba (sympto ? :intestinal/hepatic abscess: metronidazole/tinidazole followed by
paromomycin/iodoquinol )
(asympto? : paromomycin/iodoquinol)
Giardia (nitazoxanide/ metronidazole/tinidazole)
Toxoplasma gondii (serology/ PCR ||||| ) (asympto? :: no t/m necessary)
sympto?::: child pyrimethamine+sulfadiazine (e folic acid)
same for pregnant and immuno compromised .
If eye involvement , add steroids.
do not forget folic acid addition because of both drugs pyri and sulfadia
Trichinella ( mebendazole/ albendazole ) add steroids in severe disease
Amanita mushroom ( supportive care for hepatic and renal functions)
Tetrodotoxin ( puffer fish) rapid ascending paralysis with death in 4 hrs ( give resp support)
campylobactor jejuni can cause:
GBS, glomerulonephritis, igA nephropathy , erythema nodosum, hemolytic anemia (not HUS) , reactive arthritis , UTI, hepatitis, pneumonia , meningtitis.
t/m: erythromycin //azithromycin )
LACTOBACILLUS GG (reduces severity and duration of ROTA virus diarrhoea)
(for a minimum period of 7 days or untill diarrhoea resolved)
Saccharomyces boulardii ( for A/B diarrhoea, and clostridium difficile diarrhoea)
(for a minimum period of 7 days or untill diarrhoea resolved)
Clostridium difficle ( hold offending AB, start metronidazole.... 2nd line is vanco./ // NT TOX //
s. boulardii )
ETEC, EPEC, EIEC (ceftrizaone, azithro , TMP-SMX , ampicillin , cipro)
never give A/B for EHEC
Amoeba ,, metronidazole follwed by iodoquinol or paromomycin
shigella :opd ::cipro, tmp x, azithro
inpatient ,ceftriaxone
clost difficile
metronodazol oral or iv
2nd line vanco oral
salmonella diarrhea to be treated in <3mo, immunocompromised,malginancy,or systemic disease ot with ceftriaxone.
otherwise observe this diarrhea.
campylobactor jejuni : erythro ,azithro
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