Fluoroquinolones are associated with increased risk of sudden cardiac death, via the mechanism of cardiac arrhythmias due to QT prolongation.
This study published in July, includes 7657 cases of serious arrhythmia out of 2million total participants. Out of 7657 cases it was found that those patient who were advised fluroquinolones had 50percent more odds to have deadly arrhythmia irrespective of duration of onset of arrhthymia (7 days to 90 days).
Published in Resuscitation by Elsevier.
https://www.resuscitationjournal.com/article/S0300-9572(18)30736-6/fulltext
*FDA* has warned previously that fluoroqyinolones
Ciprofloxacin/Levofloxacin/Moxifloxacin etc may cause agitation/delirium/memory issues/ or even hypoglycemic comma.
So if we have a kid/adult patient having such symptoms we should keep in mind history of ciprofloxacin prescription specifically.
Lastly FDA had also issued a warning last year that these drugs can cause aortic dissection.
I couldn't assess here if these effects are dose dependant or just related to chemical nature of these drugs.
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