Serous Alveoli/acini: These are lined by serous cells, which are pyramidal (high cuboldal) In shape with spherical nucleus located in the basal half of cells. Apex of each cell contains zymogen granules and appears acidophilic. The base of each cell appears basophilic due to presence of rich rough endoplasmic reticulum. Serous cells have very fine spaces between them, which are called intercellular canallcull. Star shaped myoepithelial cells are also present between serous cells and basement membrane. Only serous acini are found in parotid and Von-Ebner salivary glands.
| Parameter | serous acinus | Mucous acinus |
| Size of acinus (diameter) | Small | Large |
| Lumen of acinus | Narrow | Wide |
| Number of cells/acinus | 5-8 | > 8 |
| size of cell | High cuboidal (pyramidal) or columnar | Cuboidal or iow columnar |
| Cell's lateral boundaries (due to secretory canallcull at cell boundaries) | Not clear (due to many canaliculi) » | Clear (due to less canaliculi) |
| Shape of nucleus | Rounded | Flattened or oval (but when empty, the nucleus is rounded) |
| Position of nucleus | Central | Basal |
| Basal striations In cytoplasm | Basophilic | Less basophilic (rich in glycoproteins and appears vacuolated due to removal of dissolved mucous) |
| Supranuclear cytoplasm | Many zymogen granules (electron- dense) | Many more mucinogen granules (electron-lucent) |
| Myoepltheilocytes | Basket cells and less in number | Spindle-shaped cells and more in number |
| secretion | Serous fluid (watery) rich in enzymes | Mucous fluid (thick or viscid) rich in glycoproteins |
| Apical microvilli | Present but Irregular | Absent |
| Amylase activity | Less | More |
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