Saturday, October 8, 2011

Histological comparison Between various Tubules of Kidney

Histological comparison Between various Tubules of Kidney

 

 

Parameter

Proximal Convoluted tubule

Loop of Henle

Distal Convoluted Tubule

Collecting tubule

Length

15 mm

 

5 mm

 

Diameter

60 nm

12-15 jim

20-50 nm

 

Lumen

Smaller (because of brush border)

Larger

Larger (because of lack of brush border)

Larger

Convoluted

More

 

Less

 

Epithelium

Simple columnar epithelium

Simple

squamous

epithelium

Simple cuboidal epithelium

Simple

cuboidal

epithelium

Number of

eells/T.S. of tubule

6-12

6-12

5-8 (but up to 20 at its macula densa)

15-20

Nuclel/T.S. of tubule

«

3-5, large, centrally located and rounded

6-12 and are

centrally located

6-8 and appear to be bulging into the lumen

15-20 and are

centrally located

Apical canaliculi

Present

Absent

Absent

Absent

Luminal surface of epithelial cells

Brush border (striated)

   

Basal striations

Lateral cell boundaries

Not clear

Not clear

Not clear

Clearly demarcated

Apical brush border of cells (microvilli)

Well-developed & possess phosphate enzymes

Only few microvilli

Not-well developed

Few

microvilli

Cytoplasmic basal

acidophilic

mitochondrial

strlatlons

Well-developed

Absent

Present but faintly stained

May be seen in some cells but poorly stained

Cytoplasm

Deeply acidophilic & more granular

Pale staining

Less acidophilic & less granular

Very pale staining

Reabsorptlon

Actively absorb glucose, amino acids & proteins

 

Absorb sodium due to aldosterone

Water

Excretion

Certain dyes & drugs (penicillin)

 

Sodium & potassium due to vasopressin

 

comparison Between various Tubules of Kidney

 

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