Wednesday, June 21, 2017

Classification of Anti Angina Drugs (Pharmacological Classification of Drugs used fro Angina Pectoris)

Drugs used in angina Pectoris are Classified as follows :

A.CORONARY VASODILATORS for angina pain
1. NITRITES AND NITRATES for angina
ACCORDING TO CHEMICAL NATURE
a) Nitrites:
Inorganic nitrites →NaNO2
Organic Nitrites→Amyl Nitrite, Ethyl Nitrite
b.Nitrates:
Nitroglycerine, Isosorbide Dinitrate
2. ACCORDING TO DURATION OF ACTION
a) Short acting nitrites
Amyl Nitrite, Nitroglycerine (sublingual), Isosorbide
b) Intermediate acting nitrites
Isosorbide Dinitrate→Chewable, Oral
Nitroglycerine→2% ointment, slow release buccal
Preparation
c) Long acting nitrites
Erythirtyl tetranitrate→Oral
Nitroglycerine slow release tras-cutaneous
Preparation, oral sustained release preparation
B. BETA BLOCKERS used for angina:
Propranolol,
Atenolol,
Nadolol
C.Calcium channel blockers used for angina:
1. Dihydropyridines:
Nifedipine, Nicardipine, Isradipine
2. Miscellaneous drugs for angina:
Diltiazem, Verapamil
THERAPEUTIC CLASSIFICATION Of Drugs USED IN ANGINA
1. Drugs for an acute angina attack
Glyceryl Trinitrate
2. Immediate pre-exertional prophylaxant
Glyceryl Trinitrate, Nifedipine
3. Long term prophylaxant:
a. beta blockers:
Propranalol, Atenolol, Metoprolol
b.calcium channel blockers
Nifedipne, Diltiazem, Verapamil
c.Long acting Nitrites:
Isosorbide Mononitrate, Isosorbide Dinitrate

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