Wednesday, June 21, 2017

Classification of Antihistamines (Pharmacological Classification of Anti-Histamines)


Anti histamines are classified as H1 receptor blockers and H2 receptor blockers. the detail of classification is as follows :

H-1 RECEPTOR BLOCKERS:-
FIRST GENERATION DRUGS:-
1) ALKYLAMINES as H1 receptor Blockers
Brompheniramine
Chlorpheniramine
Dexchlorpheniramine
Triprolidine
2) ETHANOLAMINES as H1 receptor Blockers
Carbinoxamine
Clemastine
Dimenhydrinate
Diphenhydramine
Doxylamine
3) ETHYLENEDIAMINES as H1 receptor Blockers
Tripelennamine
Pyrilamine
4) PHENOTHIAZINES as H1 receptor Blockers
Methdilazine
Promethazine
Trimeprazine
5)PIPERAZINE as H1 receptor Blockers
Cyclizine,hydroxyzine,meclizine
6)PIPERIDINES as H1 receptor Blockers
Azatidine
Cyproheptdine
7)MISCELLANEOUS drugs as H1 receptor Blockers
Cyproheptadine
Phenindamine
SECOND GENERATION DRUGS:-
Loratidine
Astemazole
Terfenadine
Cetirizine
Fexofenadine
H-2 RECEPTOR BLOCKERS:-
Cimetidine
Ranitidine
Famotidine
Nizatidine
H-3 RECEPTOR BLOCKERS:-
Thioperamide
Impromidine

THERAPEUTIC CLASSIFICATION of ANTI-Histamines
DRUGS USED IN TREATMENT OF PEPTIC ULCER:-
Cimetidine,Ranitidine,Famotidine,Nizatidine
DRUGS USED TO TREAT MOTION SICKNESS:-
Diphenhydramine,dimenhydrinate,Cyclizine,Meclizine
DRUGS USED IN TREATMENT OF INSOMNIA:-
Diphenhydramine,dimenhydrinate
DRUGS USED IN MENIERE’S DISEASE & VERTIGO:-
Cyclizine,Dimenhydrinate
DRUGS USED IN ALLERGIC DISORDERS:-
Loratidine,Fexofenadine
ANTIPARKINSONIAN DRUGS:-
Diphenhydramine,Orphenadrine
DRUGS USED AS LOCAL ANAESTHETICS:-
Promethazine,mepyramine

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