Wednesday, June 21, 2017

Classification Of Antiviral Drugs (Pharmacological classification of anti-viral drugs)


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The classification of Antiviral Drugs includes :

ACCORDING TO VIRUS ATTACKED the Antiviral Drugs are classified as :
1. Retrovirus (HIV) (Drugs acting against Retrovirus HIV)
a. Nucleoside Analogue Reverse Transcritase Inhibitors drugs
Abacavir, Didanosine,Tenofovir
b. Nonnucleoside reverse transcriptase inhibitor drugs
Delavirdine,Efavirenz,Nevirapine
c. Protease Inhibitor drugs
Amprenavir,Atazanavir,Tipranavir
d. viral Fusion Inhibitor drugs
Enfuvirtide
2. Drugs acting against Haemophilus  Influenza
a. drugs acting againt Haemophilus Strain A
Amantadine/Rimantadine
b. Haemophilus Influenza Strain A  & Haemophilus Influenza Strain B
Relenza, Tamiflu
3. Anti-Hepatitis Agents/Drugs
a. drugs acting againt Hepatitis B & C
Interferons
b. drugs acting againt Hepatitis B
Lamivudine,Dipivoxil
c. drugs acting against Hepatitis C
Ribavirin
4. drugs against Picornaviruses
Pleconaril
5. drugs against Cytomegalovirus (CMV) Infections
Ganciclovir, Valganciclovir, Cidofovir
6. drugs against Herpes Simplex Virus (HSV) & Varicella-Zoster virus(VZV) Infections
Acyclovir, Valacyclovir,Famciclovir
ACCORDING TO THE SITE OF ACTION
7. Virus polymerase
Vidarabine,Acyclovir
8. Reverse Transcriptase
a. Nucleoside Analogue Reversre Transcriptase Inhibitors
Tenovofir,Didanosine,Abacavir
b. Nonnuclesodide Reverse Transcriptase Inhibitors
Delavirdine, Efavirenz, Nevirapine
9. Protease Inhibitors
Amprenavir, Atazanavir, Tipranavir
10. RNA Mutagens
Ribavirin
11. Matrix Proteins
Amantadine, Rimantadine
12. Neuraminidase Inhibitors
Relenza, Tamiflu
13. Block Attachment & Uncoating
Pleconaril
14. Activation of Cell Defense Proteins
Interferons
Antiviral Drugs Classification ACCORDING TO CHEMICAL TYPE
15. Nucleoside Analogue antiviral drugs
Acyclovir, Vidavabine, Gancyclovir
16. Peptide Analogue antiviral drugs
Saquinavir,Ritonavir,Indinavir
17. Triazole Carboxamide antiviral drugs
Ribavirin
18. Tricyclic Amine antiviral drugs
Amantadine/Rimantadine
19. Neuraminic Acid Mimetic anti viral drugs
Relenza, Tamiflu
20. Proteins
Interferons

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