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What is calcitriol what is its biochemistry

Calcitriol is 125 dihydroxy Vitamin D

It is produced in the Kidneys from 25 hydroxy vitamin D by activation through enzyme 1 Alpha hydroxylase

Also it may be produced from 1 Alpha hydroxy D3 which are available in drops form as one Alpha drops

1 Alpha hydroxy D3 is activated in liver to 125 hydroxyvitamin d

So it is noteworthy here that in case there is chronic kidney disease with functioning liver we can give one Alpha drops and Vitamin D requirements may be fulfilled in the patient

Calcitriol is available commercially in capsule forms and in injections

Vi cap is a soft capsule that is 25 micrograms calcitriol

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