Tuesday, February 27, 2018

What is calcitriol what is its biochemistry

Calcitriol is 125 dihydroxy Vitamin D

It is produced in the Kidneys from 25 hydroxy vitamin D by activation through enzyme 1 Alpha hydroxylase

Also it may be produced from 1 Alpha hydroxy D3 which are available in drops form as one Alpha drops

1 Alpha hydroxy D3 is activated in liver to 125 hydroxyvitamin d

So it is noteworthy here that in case there is chronic kidney disease with functioning liver we can give one Alpha drops and Vitamin D requirements may be fulfilled in the patient

Calcitriol is available commercially in capsule forms and in injections

Vi cap is a soft capsule that is 25 micrograms calcitriol

No comments:

Post a Comment

Questions related to Patent ductus arteriosus

What is patent ductus arteriosus why is it more common in neonates What is frequency of patent ductus arteriosus opening after fluid bolus d...