Friday, March 1, 2013

What is the Mechanism of Autoimmune Diseases ?

 

What is the Mechanism of Autoimmune Diseases ?

 

art2B0DFailure of peripheral tolerance

–Breakdown of T cell anergy

–Failure of Activation-Induced Cell death

–Failure of T cell Medicated suppression

–Molecular Mimicry

–Polyclonal Lymphocyte Activation

–Release of sequestered Antigens

–Exposure of cryptic self and Epitope Spreading

art2B1DGenetic Factors in Autoimmunity

art2B1EMicrobial agents in Autoimmunity

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