Classification of Anti-amoebics(Classification of Drugs for amoebiasis)

Drugs for amoebiasis are classified as follows :-

Drug Treatment of Amebiasis

A) According to site of action the anti amoebics are 

1 Luminal Amebicides:

§ Dichloroacetamides
Diloxanide furoate, Paromomycin
§ Quinolines
Iodoquinol (diidohydroxyquin)
§ Antibiotics
Tetracyclin, Erythromycin

2 Systemic Amebicides

§ Emetines
Emetine HCl, Dehydroenetine HCL
§ Quinolines
Chloroquine, Iodoquinol

3 Mixed Amebicides

§ Nitroimidazoles
Metronidazoles, Tinidazole

Therapeutic Classification of Amoebiasis

1 Drugs for  Asymtomatic intestinal infection:
Luminal agent: Diloxanide furoate
Or Iodoquinol
Or Paramomycin
2 Drugs for Mild to moderate intestinal infection:
Metraonidazole/Tinidazole
Diloxanide
3 Drugs for  Severe Intestinal Infection:
Metraonidazole, Tinidazole, Diloxanide
4 Drugs for Amebic Colitis:
Metronidazole + luminal agent (diloxanide)
Tetracycline + Erythromycin
5 Drugs for Amoebic Dysentry:
Metronidazole
Diloxanide furoate
DIQ (diidoquine)
6 Drugs for Hepatic Amoebiasis:
Emetine HCL
Cholroquine Phosphate
Metronidazole
7 Drugs for Hepatic Abscess ameboma & other entraintestinal diseased:
Metronidazole (if fail then chloroquine)
Tinidazole
Diloxanide