Spinal muscular atrophy may be summarised as it is a disease of anterior horn cells it is progressive in nature and is inherited as autosomal recessive trait
There is generalized weakness of skeletal muscle which may or may not involve respiratory muscles the baby is flaccid and at some stage of the disease there is involvement of respiratory muscles and or diaphragm
There are three types of spinal muscular atrophy
Type 1 is early infantile form which presents before 6 months of age it is a very severe form search dead survival beyond 3 years is uncommon
Type 2 of spinal muscular atrophy is a late infantile form
Type 3 spinal muscular atrophy is juvenile onset form
Type 1 Is also called werdnig Hoffman disease
Type 3 is also called kugelberg velander disease
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