Benzodiazepine poisoning
Dr Usama Amjad
Dr Usama Amjad
There is
usually a history of benzodiazepine drug intake by elderly at home and so the
dose taken by child can be inquired by missing tablets in pack. Benzodiazepine
poisoning is rare as iatrogenic preprocedural sedation.
Signs and symptoms
Signs and symptoms
Dizziness,drowsiness,confusion,blurred
vision,unrespnsiveness
ASOC,Respiratory depression,cyanosis,Hypotension,Ataxia
Hypotonia,Coma,Weakness,amnesia
Investigations
SERUM GLUCOSE level
Septic profile
SERUM GLUCOSE level
Septic profile
Workup for CNC
infection
ECG
Save urine and serum samples for forensic workup
PREGANANCY TEST (IN WOMEN OF CHILDBEARING AGE
Save urine and serum samples for forensic workup
PREGANANCY TEST (IN WOMEN OF CHILDBEARING AGE
MANAGEMENT
Admit the patient
counsel parents
get high risk consent
get MLC
Admit the patient
counsel parents
get high risk consent
get MLC
Maintain Airway and breathing (clear the secretions , and may need to pass ETT to get adequate chest rise ), Assess and maintain circulation. The heart rate and blood pressure mostly improves as airway and breathing are secured.
Do stomach wash till clear stomach contents are there.
SPECIFIC
ANTIDOTE IS FLUMAZENIL
DOSE 0.01mg IV given over 30 seconds , may repeat after 1 minute, to maximum cumulative dose of 1 mg.
May need to give repeat bolus doses.
DOSE 0.01mg IV given over 30 seconds , may repeat after 1 minute, to maximum cumulative dose of 1 mg.
May need to give repeat bolus doses.
It may
precipitate seizures .
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