Monday, April 16, 2018

Revised Jones Criteria for Diagnosis of Rheumatic Fever : 2015 : Summary easy to understand

Revised Jones Criteria for Diagnosis of Rheumatic Fever
                                                  
                                                                Dr Efra Abbas

We in Lahore, Pakistan , have a High Risk population for occurrence of Rheumatic Fever.                  

•         Low risk population
▫         ARF incidence <2 per 100,000
•         High risk population
▫         Children not clearly from a low-risk population are at moderate to high risk depending on their reference population
▫         >2/100000 arf or rhd prevlance >1 /1000

Major Manifestation
Minor Manifestations
Evidence of Antecedent Grp A Streptococcal infection
Carditis
Polyarthritis
Erythema marginatum
Subcutaneous nodules
Chorea
Arthralgia
Fever
Elevated ESR/CRP
Prolonged PR interval
Positive throat culture or Rapid Streptococcal antigen test
Elevated or increasing streptococcal antibody titer


Initial Attack:
•         2 major
•         1 major and 2 minor
•         With evidence of recent GAS

Subsequent Attack :
•         2 major
•         1 major ,2 minor
•         3 MINOR IN HIGH / MODERATE RISK POPULATION
•         Plus preceding GAS

CARDITIS:
2 major
•         1 major ,2 minor
•         3 MINOR IN HIGH / MODERATE RISK POPULATION
•         Plus preceding GAS

So,
Echocardiography/Doppler testing should be performed to assess whether carditis is present in the absence of auscultatory findings, particularly in moderate- to high-risk populations and when ARF is considered likely

ARTHRITIS:
Migratory polyarthritis , large joints , disproportionate pain, non deforming
•         Low risk : polyarthritis
•         High risk :
▫         Monoarthritis in the absence of prior inflamatory therapies
▫         Polyarthralgia  when other causes are excluded

Minor criteria: low risk population
•         Minor criteria:
•         Polyarthralgia
•         fever (≥38.5° F) 101.3 deg Fahrenheit
•         sedimentation rate ≥60 mm
•          C-reactive protein (CRP) ≥3.0 mg/dl
•         prolonged PR interval (unless carditis is a major criterion
•          
Minor criteria: high risk
•         Minor criteria:
•         fever (≥38° F)  100.4 deg Fahrenheit
•         sedimentation rate ≥30 mm
•          CRP ≥3.0 mg/dl
•         prolonged PR interval (unless carditis is a major criterion)

Evidence of preceding Streptococcal infection
•         Increased or rising anti-streptolysin O titer or other streptococcal antibodies (anti-DNASE B) (Class I, Level of Evidence B).
•          A positive throat culture for group A β-hemolytic streptococci (Class I, Level of Evidence B).
•          A positive rapid group A streptococcal antigen test in a child whose clinical presentation suggests  streptococcal pharyngitis (Class I, Level of Evidence B)
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