COMMON PAEDIATRIC DRUGS DOSES:

 

The young physician starts life with 20 drugs for each disease, and the old physician ends life with one drug for 20 diseases.

COMMON PAEDIATRIC DRUGS DOSES:

                                  Revision 2017-  M Tauseef Omer

ANTI-PYRETIC,ANALGESC,ANTI-INFLAMATORY..

DRUG	Brand Name	Dose	Indications
Acetaminophen (paracetamol)	Calpol syrup. Panadol drops	10mg/kg/dose every 6 hours	Syrup 120mg,160mg/5ml		Tablet/Drops 80mg/ml, Tab 200,400mg	Antipyretic analgesic
Ibuprofen	Syrup.Brufen	10mg/kg/dose every 6 hours	100mg/5ml		*200mg *400mg	Antipyretic analgesic
DEXYBRUFIN	DEXY,TERCICA	5mg/kg/dose  every 6 hours	100mg/5ml			Antipyretic analgesic
Aspirin	disprin	90-130mg/kg/day,6hrly			Tab.300mg	Anti- inflamatory
Nalbuphine	nalbine	0.1-0.2mg/kg/dose ,6hrly,IV,IM,SC	Inj 10-20/ml
Diclofenac	Dicloran,voltran	>1-3mg/kg/day	Inj 75mg/3ml		Tab 50mg
Morphine		0.15-0.2mg/kg/dose, IV,IM,SC	Inj 15mg/ml
Pancuronium	Pavulon	60-100mcg/kg then 10-20mcg/kg/dose ,20-60mint	Inj 2mg/ml		Muscles relaxant	Intubation Only by seniors..
Baclofen	LioresaL, baclotab	10-15mg/day,8hrly For 3 days			Muscles relaxant

ANTIEMETICS:

Drug	Brand Name	dose	indications
DIMENHYDRINATE	Inj./syrup.Gravinate	0.5mg/kg/dose every 6 hours	12mg/5ml			Antiemetic
Metoclopramide	Inj./syrup maxolon. Inj.metomide	0.2-0.5mg/kg/day every 6 hours	5mg/5ml	10mg		Antiemetic Can Cause sever Dystonic Reactions Not Recommended  in paeds anymore.
Domperidone	Syrup.Peridone. Syrup Domel Inj.motilium	0.5mg/kg/dose every 6 hours	5mg/5ml	10mg		Antiemetic Can cause severe dystonic reactions Not Recommended  in paeds anymore.
ONDANSETRON	Inj.tab Onset	0.15mg/kg/dose	2mg/ml	2,and 4mg		Chemoth-vomiting

                                                                   ANTIBIOTICS

QUINOLONES:

drug	Brand Name	Dose	strength			indications
Ciprofloxacin	Syrup.novidat Tab.novidat. Syrup.Gavel. Syrup.Mytel	ORAL:20-30mg/kg/day every 8-12hrs. I/V:4-15mg/kg/day every 8-12hourz	*125mg/5ml *250mg/5ml	Tab.100mg ,250mg and ,500mg		Typhoid. UTI’S.
Nalidixic Acid	Susp.negram. Tab.negram	55mg/kg/day every 6 hourly	250mg/5ml	500mg		Lower UTI’s

CEPHALOSPORINS

Drug	Brand Name	Dose	indications
1st Generation
Cephalexin	Ceporex	25-100mg/kg/day every 6 hrz.	*125mg/5ml *250mg/5ml	Drops:125mg/ml
Cephradine	Syp.velosef	50-100mg/kg/day every 6 hrz	*125mg/5ml. *250mg/5ml	250mg/vial. 500mg/vial.
2nd generations
Cefaclor	Syp.ceclor	20-40mg/kg/day every 8 hrly	125mg/5ml. 250mg/5ml.	DROPS:125mg/ml.
Cefuroxime	Inj.zinacef Syp zecef	50-100mg/lg/day every 8hrly.	125mg/5ml, 250mg/5ml	250mg/vial. 750mg/vial.
3rd generations
Ceftriaxone	Inj.Rocephin. Inj.oxidil. Inj.dayline. Inj.pathocef. Inj.titan	50-75 mg/kg/day every 12 hrly. Meningitis:100mg/kg/day every 12hrly.		250mg/vial. 500mg/vial. 1g/vial.		Liver toxity
Cefotaxime	Inj.claforan. Inj,Yarker.	100-200mg/kg/day  every 12hrly		250mg/vial 500mg/vial.1g/vial.		Renal toxicity
Ceftazidime	Inj fortum	100-200mg/kg/day.8hrly				Anti pseudomonas
CEFIXIME	SYP.cefspan. Syp.caricef. Syp.cefiget. Syp.synocef. Syp.cef-od Syp.cefim.	10mg/kg/day in 12hrz.or 24hrz.	100mg/5ml. SD.200mg/5ml
Amoxicillin	Syp.Amoxil. Syp.suprmax	20-40mg/kg/day every 8-12hrz.	125mg/5ml. 250mg/5ml	Cap.250mg and 500mg
Amoxicillin-clavulanate	Syp/inj. Augmentin, Calamox	20-45mg/kg/day every 8-12hrs. 80-90mg/kg/day for otitis media.	156mg/5ml. DS syrup 312mg/5ml 457mg/5ml	Tab 357mg,625mg, and 1gm
AMPICILLIN	Syp.inj Penbritin	100-300mg/kg/day every 8 hrly	125mg/5ml  250mg/5ml	125mg/5ml .250mg/5ml		Gram positive..
Metronidazole	Tab.,Syrup,Inj.Flagyl	35-50mg/kg/day every 8hrly	Syr.200mg/5ml	Tab 200mg,400mg
Meropenem	Inj.meronem	60-120mg/kg/day,every 8hrly (as infusion in 20 c.c Normal Saline over 30 minutes)	500mg and 1Gm
Vancomycin	Inj.vanco	40-60mg/kg/day, every 8hrly (as infusion in 20 c.c Normal saline over 45 minutes) > Much slower than Meropenem.	Inj:500mg/vial,1g/vial.			Staph and resistan gram positive infections
AMIKACIN	Inj.gracil	7.5-10mg/kg, 8 hrly	25mg/ml, 250mg/ml
Tazobactem+Piperacillin	Tanzo	150-300mg/kg/day,8hrly	2gm pipercacillin			Nosocomial pneumonia
PENCILLIN-G	Inj.Benzyl-pencillin	1-4 lac/kg/day,6hrly	5-10 lac     units/vial	Don’t Forget Test Dose		Streptococcal infections
Benzathine Penicillin	Penidure LA, INJ Benzibiotic	6/12 lac  unit IM,3WEEKLY	Inj 6/12 lac	Don’t Forget Test Dose		Rheumatic fever prophylaxis
Clarithromycin	Susp Klaricid,pathocin,	7.5-15mg/kg/day,12hrly (if i/v,, then as infusion over 30 min)	125mg/5ml	Tab.500mg		IV INFUSION IN SALINE OVER 4 HR
Azithromycin	Syp Azit,zeenase	10mg/kg,OD,3days	200mg/5ml
Artemether	Artem	3.2mg/kg IM state,then 1.6mg/kg ,OD,4days	Inj 40mg. Cap.80mg			malaria
Atrtemther+lumefantrine	Comether, arceva	3mg/kg/day	Syp.15mg artemether/5ml (15/90) (30/180) Tab 40/240 Tab 80/480
Quinine sulfate		IV 10mg/kg loading over4 hr then same as 8hrly	Oral..double dose			Cerebral malaria.
Chloroquine	nivaquine	10mg/kg stat then 5mg/kg aftr 6 hr then 5mg/kg OD for 2days.	50mg/5ml	TaB 150MG		Prophylaxis,5mg/kg,once weekly.
		ANTITUBERCULOUS Give before breakfast.
ISONIAZID	ISONEX	10mg/kg/day,OD	Syp50mg/5ml	Tab.100mg		Prophylaxis5-10mg/kg/day OD
RIFAMPICIN	Rimactane,rifdin	15mg//kg/day OD,1/2HR b4 Breakfast	Syp.100mg/5ml	Tab.300, 450mg		Nesseria carrier..10-20/kg/day OD,4days
PYRAZINAMIDE		30mg/kg/day,OD	Syp.250mg/5ml	500mg
ETHAMBUTOL	myambutol	25mg/kg/day OD >5year		40Omg
STREPTOMYCIN	-	20-40mg/kg/day,OD,IM	Inj 1G
Myrin	Rifampicin/ INH/ Ethambutol	150/ 75/ 300
Myrin-P	Rifampicin/ INH/ Ethambutol/ Pyrazinamide	150/ 75/ 275 400 Other Dosage available as : 120/ 60/ 225/ 300
Trimethprim+sulfamethoxazole	septran	8-10mg/kg/day,12hrly UTI prophylaxis 2mg/kg ,OD	Syp TMP 40mg	Tab 100mg\ DS..200mg		PCP..10-20mg/kg/day UTI,BOILS
		ANTIVIRAL
ACYCLOVIR	Zovirax,aclova Acylex	20 mg /kg/dose (give 8 hourly) as infusion over 60 minutes	Syp 200mg/5ml	Inj 250mg		Herpes simplex and varicella zoster Encephalitis (The dosage for skin lesion is 10mg/kg/dose given 8 hourly)
		ANTIHELMINTHIC
MEBENDAZOLE	Vermox Vermol	100mg,12hrly,3days >2yr children	Syp 100mg/5ml	Tab 100 mg Tab 500 mg		antihelminthics
Albendazole	zentel	200mg,single dose  >2 yr children	100mg/5ml	Tab.200mg		antihelmintjics
Levamisol	ketrax	2.5mg/kg ,single dose	40mg/5ml			antihelminthics

    

INOTROPIC  AGENTS

DOPAMINE	Inj.Inotropin	5-15mcg/kg/min or 0.012*dose*weight	200mg/5ml
DOBUTAMINE	Inj.Dobutrex	10-20mcg/kg/min 0.01*dose*weight (These formulae are for Dobutrex250mg/5ml Dopamine 200mg/5ml - Do check the strength of your injections before you advise on t/m ticket)	250mg/5ml
The Above two Inotropes, Dobutamine and Dopamine are given as a continuous infusion for whole 24 hours. Never stopped even if the patient is being transported or being given a blood transfusion or undergoing any procedure. If  these two drugs do not give response , then Infusion of  NorEpinephrine (0.1 micro gram /Kg/min is started along with these)
DIGOXIN	LANOXIN	IV Digitilizing dose 0.10-0.30mg/kg divided in fractions ot PO 0.04mg/kg divided ib fractions as	Give half dose of total dose stat. Then1/4th 8hr later, Then1/4th 16hr later Thengive 1/4th as maintenance dose after 24 hr IV OR PO..	OR maintence 0.1-0.015mg/kg/day 12hry
Adrenaline	1:10000 sol..used (made by dilution)	0,1ml/kg/dose IV 5mint upto 0.5ml/kg	Inj 1:1000, 1ml/1mg 1mg is 1000 Units
Atropine		0.02mg/kg/dose		Sinus bradycardia and organophosphorus
		ANTIHYPERTENSION
Propranolol	inderal	0.5-1mg/kg/day6-12hrly	TOF..0.15-0.25mg/kg/dose slow IV repeat after 15 mint. PO2mg/kg/day,6Hrly
Nifedipine	Adalate	0.25-0.5mg/kg/dose PO,SL,6hrly	Tab.20mg	Cap.10mg
Methyledopa	aldomate	10mg/kg/day,6-12hrly upto65mg/kg/day	Inj50mg/ml,tab.250,500mg
Captopril	Capoten,capase	0.5-0.6mg/kg/dose,6hrly Upto 6mg/kg/day		Tab12.5mg,25mg
Sodium Nitropruside	Nipride	0.25-6ug/kg/min
Diaxoxide	Hyperstat	IV 3-5mg/kg repeat aftr 15 mint	15mg/ml
Hydralazine	aspresoline	0.15mg/kg/dose IV, Repeat 90 mint
		ASTHMA
Salbutamol	Ventoline	Oral0.2-0.4mg/kg/day,8hrly	Syp.2mg/5cc,sol.5mg/ml,	Nebulization 0.1-0.2mg/kg/dose
Aminophyline		5mg/kg IV ovr 20 mint.	Inj 250mg/10cc
		Inhaler
Beclomethasone	becotide	50-100mcg,2-4 times a day,MAX 10 puff daily	50ug/puff
Salbutamol	ventoline	2 puff,2-4 times aday	100 ug/puff
Fluticasone	flunisolide	4 puff aday
		Nebulization
Salbutamol	Resp. solution	<1 yr  0.1mg/kg/dose in 1.5cc Normal Saline  (nebulize 4 to 6 hourly) 1-5 Yr  2.5mg/dose made in NS (nebulize 4 to 6 hrly) >12 yr 2.5  to  5 mg /dose (nebulize 4 to 8 hrly)	Comes in variable strength in our ICU. usually, 5mg/1cc solution May take it with syringe	Ref. Harriet Lane 20th Ed
Ipratropium	Atrovent2%	<12 yr  0.25 mg /dose repeat after 20min, then 2-4 hrly as needed. >12 yr 0.5mg /dose repeat after 30 min, the 2 to 4 hrly as needed	Comes in variable strength in our icu, Usually, 0.25mg/ml	Ref. Harriet Lane 20th Ed
Beclomethasone	Clenil Aerosol	0.04 mg nebulized X B.D	Check strength on Vial that is available in ICU and dilute in 2cc Normal Saline.	Ref. Harriet Lane 20th Ed
Epinephrine		Croup: (0.5mL/Kg of 1:1000 solution diluted in 3ml Normal Saline )(with maximum dose as : 4Year or less > 2.5ml/dose More than 4 yr 5ml/dose Post Endotracheal Extubation : 0.1 ml / kg of 1:1000 in 1.5 cc normal Saline		Ref. Harriet Lane 20th Ed
		ANTICOAGULANTS
Heparin		50unit/kg IV bolus,then infusion 10-25/kg/hr		Adjust according to APTT
Warfarin		0.1mg/kg/day PO,	Maintence 0.05-0.34mg/kgday,6hrly	Adjust according to PT
		DIURETCS
Mannitol 20%		Diuretic.0.25mg/kg/dose in 30 After checking B.P	20gm/100ml	Cerebral edema.initial 0.5-1gm/kg/dose then.0.25-0.5mg/kg/dose
Acetazolamide	Diamox 250 mg tab	Diuretic (30 mg/kg/day) divided 8H or 6 H
Frusemide	lasix	1-2mg/kg/dose,BD,TDS upto 6mg/kg.dose,	Inj1ml/10mg,tab20,40mg
Spironolactone	aldactone	1-3mg/kg/day,12hrly	25/100mg
Naloxone		0.01-0.2mg/kg/dose,at 3mint interval	0.04mg/ml	Morphine poisoning

ANTICONVULSANTS/SEDATIVES:

DIAZEPAM	Inj.Valium	0.1-0.5mg/kg/dose. If given i/v, give slowly over 60 seconds	Inj.10mg/2ml vial, Tab.2mg,5mg,10mg.	Fits/epilepsy
PHENOBARBITONE	Debritone,pheno	Loading:20mg/kg stat, Mainten.:4-8mg/kg/day every 12-24 hrs	Tab.30mg Syp.20mg/5ml Inj 200mg	Fits/epilepsy
MIDAZOLAM	Inj.Dormicum	0.1mg/kg/dose,every 5mint upto 5 time..max 0.6mg/kg If given i/v, give slowly over 60 seconds	5mg/5ml	Start with Infusion 0.1-0.2ug/kg/min To get response , may increase to 18ug/kg/min
PHENYTOIN	DILANTIN Syp epitoin	Load with inj phenytoin 20mg/kg/dose in 20c.c normal saline over 20min. then; 5-10mg/kg/day,BD	Syp 125mg/5ml	epilepsy
CLONAZEPAM	RIVOTRIL	0.01-0.03mg/kg/day,8hrly,increase 0,5mg/day for 3days upto 0.3mg/kg/day	Drops2.5mg/ml ?? tab 0.5 mg tab  2mg	epilepsy
Sodium valproate	Epival,epilim	10mg/kg/day,12hrly,increase5mg/kg/week upto 60mg/kg/day (hepatic side effects)	250mg/5ml Tab 250mg Tab 500mg	epilepsy
Levetiracetam	Lerace Klevra Levitra	10 mg/kg/dose X 12H May increase to max 30mg/kg/dose X 12… increase 2 Weekly if tolerated . (Renal Side effects)	100mg/ml drops Tab 250mg tab 500mg Tab 750 mg
LAMOTRIGINE	lamictal	2mg/kg/day,12hrly for 2week then 5hen 5mg/kg/day	Tab25,50,100mg	Adjuvant epilepsy
TOPIRAMATE	TOPAMAX	>2yr ..25mg at nite..then increase 1-3 weeks by  1-3mg/kg/day upto5mg/kg/day	Tab.25,50mg	Adjuvant epilepsy
CHLORAL HYDRATE		For Sedation : 8mg/kg/dose	250mg/5ml  ??	sedative
	ANTIALLERGIC	AND STEROIDS
Chlorpheniramine	Tab/Syp.Avil.	1-2mg/kg/day every 6 hrz.or 1TSF for 10kg. <10kg ½ TSF. >10kg 2TSF.	15mg/5ml tab 25mg tab 50mg tab 75 mg	22.7mg/2ml
Loratidine	Syp.Antial,lorel	0.2-0.3mg/kg/dose,OD	5mg/5ml	Tab 10mg
Cetrizine	Rigix,zyrtec	0.2-0.3mg/kg/dose,OD	5mg/5ml	10mg
Diphenhydramine	benadryl	4-6mg/kg/day,6hrly IV,PO	13.5mg/5ml
Hydrocortisone	Inj.Solucortef	Septic shock:35-50mg/kg/d,4-6hrly Acute asthma 5mg/kg/dose stat,1-2mg/kg/day 6hrly		100mg/2ml. 250mg/2ml. 500mg/4ml
		Stress dose Hydrocortison in CAH: if mild stress(like URTI/AWD/etc), increase dose to 3 times. if comes in crisis/obtunded, then, 100mg/m2 per day		Must get Endocrinology consult.
Dexamethasone	decadron	Anti-inf..0.3mg/kg/day,6-12hrly, Meningitis..0.6mg/kg/day,6hrly for 4 days Cerebral edema..loading 1-2mg/kg/dose once then 0.2-0.5mg/ kg/day,6hrly Before Extubation.. 0.25mg-0.5mg/kg/day,8hrly	4mg/ml..	Tab 0.5mg
Prednisolone	Deltacortil Syp Steron (15mg/5ml)	Asthma and asthma 1-2mg/kg/day, PO, Nephrotic Syndrome: Stat with 60mg/m2 /Day Formula to Calculate Surface area from weight (x)  is : S.A = (4x + 7) / (90 + x)        = _____ m2	Tab Deltacortil             (Tab 5mg) Syp Steron                     (15mg/5ml) Syp Neupred
Methyl Prednisolone acetate (Depo-Medrol) Methyl Predniolone Sodium Succinate (Solumedrol)		Acute asthma..2mg/kg/dose,6hrly. Acute spinal cord injury 30mg/kg in 15 mint folowed by 5mg/kg/hr for 23 hr. Also indicated in : Sensitivity Transplantation Cerebral Edema UC crohns Aspirationpneumonia SJS rheumatoid arthritis Osteoarthritis Dermatoses Hay Fever Collagen Disorders		Inj 40mg,125mg,500mg Tab 2,4,,8,16,32 mg
NEWER ADDITIONS
Fluconazole	Load with 12mg/kg/dose, then 6mg/kg/day(24 hours after loading dose)	Antifungal	Both syrup and Iv forms available.	Syp Diflucan(50mg/5ml) Syp Fzole
Ursodeoxycolic Acid	Neonate: 10mg/kg/day (OD dose) Child: 20 mg /kg/day (divided BD)	Advised in cholestatic jaundice		Syp Urso (250mg/5ml)
Rifaxamine	10mg / kg /dose (OD) per NG	Advised in Hepatic failure to clear GUT off ammonia producing bacteria.		Tab Rifaxa 200mg Tab Nixaf 550mg Tab Xifaxa 550mg
Sodium benzoate	1ml per Kg per NG	Advised in hepatic failure to bind free ammonia in GIT		May be acquired from Children Hospital Lahore’s Pharmacy
Nitazoxanide (100mg/5ml)	1-3 year: 100mg PO BD for 3 days 4-11 year: 200mg PO BD for days >12 years  500mg PO BD for 3 days	Advised in chronic giardiasis		Syp NT-TOX (100mg/5ml) Tab NT-TOX 500mg Syp Atizox(100mg/5ml)